Gaasyendietha was famous in Seneca mythology and while it lived in rivers and lakes, it also flew in the sky with its giant body and it used to spew fire. Its horn was rumored to be a powerful aphrodisiac, so the natives often tried to chant and perform magical summons to draw the serpent and harvest its horn.
Stvkwvnaya was a horned sea serpent from Seminole mythology.Kinepeikwa or Msi-Kinepeikwa was a massive land serpent that gradually grew by repeatedly shedding its skin until it eventually dove into a lake.